Product details

LungCancer Panel

Catalog Number:

#1001922 (16 rxn)
#1001921 (96 rxn)

LungCancer Panel v1.0 is specifically designed for lung cancer research. This panel involves 24 genes, including full coding regions from 19 genes and non-exonic regions with frequent fusion occurrence in lung cancer.

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Gene List

Genes with coding regions covered

*ALK*	*BRAF*	*CD274*	CD74	*EGFR*	*ERBB2*	EZR	*FGFR1*	*FGFR2*	*FGFR3*	*KRAS*	*MET*
*NRAS*	*NTRK1*	*NTRK2*	*NTRK3*	NUTM1	*PDCD1LG2*	*PDGFRA*	*PIK3CA*	*RET*	*ROS1*	SDC4	SLC34A2

Genes with full coding regions shown in bold.

Performance

Table 1. Performance of LungCancer Panel v1.0

Platform

On-target rate (%)

Duplication (%)

% target

> 0.2 x mean

% target

> 0.5 x mean

% target

> 1 x mean

Fold 80 base penalty

MGI

92.75

6.20

99.21

96.21

52.12

1.28

Illumina^®️

93.98

12.21

99.98

97.92

52.14

1.27

The DNA libraries were prepared from human genomic DNA (Promega, G1521). 1 M read pairs were subsampled for the analysis.

Fig 1. Evaluation of LungCancer Panel v1.0 on the analysis of SNVs and indels. The DNA libraries were prepared from Onco SNV Multiplex 1-25% gDNA (GeneWell, GW-OGTM004) using NadPrep library kits. The enriched libraries were sequenced either on HiSeq X Ten (PE150) or DNBSEQ-G400 (PE100).

For research use only. Not for use in diagnostic procedures.

Catalog#	Color Of Tube Cap	Item	Volume	Package/Storage
1001922		LungCancer Panel v1.0, 16 rxn	70 μl×1	–20℃
1001921		LungCancer Panel v1.0, 96 rxn	415 μl×1	–20℃

Product	Catalog#
LungCancer Panel v1.0, 16 rxn	1001922
LungCancer Panel v1.0, 96 rxn	1001921

For research use only. Not for use in diagnostic procedures.

Product Sheet

Application Note

Demo Data

LungCancer Panel v1.0 GW-OGTM001 Illumina.1

Title: LungCancer Panel v1.0 GW-OGTM001 Illumina.1 DNA library was created from Onco Structural Multiplex 5% gDNA (GeneWell, GW-OGTM001) using Nanodigmbio NadPrep library preparation kit (for Illumina). The library was enriched in capture using the LungCancer Panel v1.0, then sequenced.

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LungCancer Panel v1.0 GW-OGTM001 MGI.1

Title: LungCancer Panel v1.0 GW-OGTM001 MGI.1 DNA library was created from Onco Structural Multiplex 5% gDNA (GeneWell, GW-OGTM001) using Nanodigmbio NadPrep library preparation kit (for MGI). The library was enriched in capture using the LungCancer Panel v1.0, then sequenced.

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LungCancer Panel v1.0 GW-OGTM004 Illumina.1

Title: LungCancer Panel v1.0 GW-OGTM004 Illumina.1 DNA library was created from Onco SNV Multiplex 1-25% gDNA (GeneWell, GW-OGTM004) using Nanodigmbio NadPrep library preparation kit (for Illumina). The library was enriched in capture using the LungCancer Panel v1.0, then sequenced.

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LungCancer Panel v1.0 GW-OGTM004 MGI.1

Title: LungCancer Panel v1.0 GW-OGTM004 MGI.1 DNA library was created from Onco SNV Multiplex 1-25% gDNA (GeneWell, GW-OGTM004) using Nanodigmbio NadPrep library preparation kit (for MGI). The library was enriched in capture using the LungCancer Panel v1.0, then sequenced.

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